Build the science that shapes the future of human health.
Application closing date: 28.06.2026

Join a place where ambitious science thrives
Human Technopole (Milan) is a rapidly expanding life science institute where international researchers and cutting-edge technologies converge to accelerate biomedical discovery. Our mission is to transform bold scientific ideas into advances that improve human health.

Within this mission, the LaJoie lab, as part of the Molecular Cell Research Centre, studies how proteins of the nuclear envelope function to promote human health. By doing so, we can understand how their dysregulation results in diseases such as muscular dystrophy and cardiomyopathy. With the combination of specialized resources and expertise at Human Technopole, we are uniquely able to address these questions and the molecular and cellular level.

Your mission

The LaJoie Group seeks a Postdoc to identify novel protein-protein interactions using in situ crosslinking mass spectrometry, characterize disease-relevant protein mutations biochemically, and perform protein perturbation experiments in cells to understand molecular pathways of diseases of the nuclear envelope. The position is suited for candidates from the fields of biochemistry, cell biology, and proteomics, who are interested in integrating diverse methodologies in a highly collaborative environment.

Grow your skills
You will enhance your scientific skills and professional skills in a research environment that spans multiple disciplines and specialized methodologies uniquely possible at Human Technopole. The role therefore provides the opportunity to integrate advanced techniques in cell biology (e.g. cellular perturbation approaches, light microscopy), biochemistry (e.g. single molecule studies), structural proteomics (e.g. crosslinking mass spectrometry), and the possibility to work with disease-relevant cellular model systems (e.g. iPSCs). Through mentorship and collaboration, you will strengthen your ability to formulate meaningful biological questions, design and test hypotheses, integrate diverse experimental data, and translate experimental findings into mechanistic and clinically relevant insight.

Human Technopole supports career development through training, mentoring and dedicated learning opportunities.

Key tasks and responsibilities

• Conduct innovative research activities and develop tailored methods and tools to support project objectives, ensuring accurate documentation of all research processes and findings.
• Generate, analyze, and maintain high-quality experimental data to support scientific publications, grant applications, and research reporting.
• Contribute to the preparation of manuscripts, figures, and scientific communications for publication in peer-reviewed journals and presentation at conferences and seminars.
• Mentor students and junior staff by providing technical guidance, training, and support in experimental procedures and data acquisition activities.
• Collaborate closely with internal teams, external experts, and research leaders to design research plans, manage experiments, and promote scientific knowledge exchange and project development.

Job requirements

Essential requirements
On the agreed hiring date, the candidate must fulfil all the following conditions:

• Ph.D. for which the thesis project was in biochemistry, molecular cell biology (or wet lab approaches applicable to molecular cell biology), proteomics, or a related topic
• Proven ability to lead projects independently.
• Experience analysing biological datasets.
• Experience in interdisciplinary settings, with a collaborative approach to advancing projects.
• Ability to write publications, present findings, and effectively communicate research to diverse audiences, including peers from different disciplines.
• Fluency in English (HT is an international research institute).

Preferred requirements

• Experience working with mammalian cell culture
• Light microscopy experience

Organisational and social skills

• Sensitivity and respect for diversity in a multicultural and multi-ethnic work environment.

• Intellectual curiosity, creativity, and ambition to explore biological questions
• Strong analytical skills.

At HT, your discoveries contribute to a global effort to improve human health.

Why Human Technopole
HT offers an international and dynamic workplace, competitive welfare provisions, flexible working policies and relocation support. Researchers moving to Italy may benefit from attractive tax benefits. We promote work–life balance and provide parental support initiatives.

How to apply
Submit:
• CV (English)
• Motivation letter (English)
• Contact details of two referees

This is a 4-year contract offered under CCNL Chimico Farmaceutico, Level B2

Salary: up to € 43.000,00 depending on the candidate’ seniority.
The position is based in Milan, Italy, within our vibrant international campus.
We strongly encourage applications from candidates belonging to protected categories (L. 68/99).